INABILITY OF A STRAIN OF SEOUL VIRUS TO TRANSMIT ITSELF VERTICALLY IN RATS

Authors:
  • HUHiroshi Ueno
    Hiroshi Ueno
  • SMShigeru Morikawa
    Shigeru Morikawa
  • KSKazuyoshi Sugiyama
    Kazuyoshi Sugiyama
  • TKToshihiko Komatsu
    Toshihiko Komatsu
  • TKTakashi Kitamura
    Takashi Kitamura
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Abstract
SR-11 strain of Seoul virus was inoculated into new-born female rats. These rats at the age of 13 weeks were mated with uninfected male rats. The virus was transmitted to the male rats, but the offsprings were not infected from their mather rat owing to the maternal antibody. No intrauterine transmission of the virus was observed. We assumed that SR-11 type strain of Seoul virus could not be disseminated among rats in nature.