Protein kinases A and C regulate amyloid-β degradation by modulating protein levels of neprilysin and insulin-degrading enzyme in astrocytes
Authors:
- 1 May 2021
- journal article
- research article
- Published by Elsevier in Neuroscience Research
- Vol. 166, 62-72
Abstract
No abstract availableKeywords
Funding Information
- JSPS KAKENHI of the Grant-in-Aid for Young Scientists B (25870906)
- Private University Research Branding Project (18K08833)
- Special Research Grant of Hokuriku University, Japan
This publication has 50 references indexed in Scilit:
- Cell Surface Expression of the Major Amyloid-β Peptide (Aβ)-degrading Enzyme, Neprilysin, Depends on Phosphorylation by Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase (MEK) and Dephosphorylation by Protein Phosphatase 1aJournal of Biological Chemistry, 2012
- Neuropathological Alterations in Alzheimer DiseaseCold Spring Harbor Perspectives in Medicine, 2011
- Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's diseaseNeurobiology of Aging, 2010
- Expression and functional profiling of neprilysin, insulin‐degrading enzyme, and endothelin‐converting enzyme in prospectively studied elderly and Alzheimer’s brainJournal of Neurochemistry, 2010
- The role of microglia in amyloid clearance from the AD brainJournal of Neural Transmission, 2010
- Neprilysin: An Enzyme Candidate to Slow the Progression of Alzheimer's DiseaseThe American Journal of Pathology, 2008
- Activation of protein kinase C modulates BACE1-mediated β-secretase activityNeurobiology of Aging, 2008
- A limited role for microglia in antibody mediated plaque clearance in APP miceNeurobiology of Disease, 2007
- Down‐regulation of cAMP‐dependent protein kinase by over‐activated calpain in Alzheimer disease brainJournal of Neurochemistry, 2007
- Regulation of Alzheimer's disease amyloid-β formation by casein kinase IProceedings of the National Academy of Sciences, 2007