UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment
Open Access
- 9 April 2022
- journal article
- letter
- Published by Springer Nature in Leukemia
- Vol. 36 (6) , 1676-1680
Abstract
No abstract availableKeywords
Funding Information
- Deutsche Forschungsgemeinschaft (CATCH-ALL, CATCH-ALL, CATCH-ALL, CATCH-ALL)
- José Carreras Leukämie-Stiftung (01R/2016)
This publication has 15 references indexed in Scilit:
- The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 VulnerabilityCancer Cell, 2019
- PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemiaLeukemia, 2019
- Driver Fusions and Their Implications in the Development and Treatment of Human CancersCell Reports, 2018
- ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor GrowthMolecular Cell, 2016
- FusionCatcher – a tool for finding somatic fusion genes in paired-end RNA-sequencing databioRxiv, 2014
- The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemiaLeukemia, 2009
- Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemiaBlood, 2008
- The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesisJournal of Clinical Investigation, 2007
- Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancerJournal of Clinical Investigation, 2005
- Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9Genes & Development, 2003