Articular cartilage tissue engineering
Authors:
- 1 May 2009
- journal article
- review article
- Published by British Editorial Society of Bone & Joint Surgery in The Journal of Bone and Joint Surgery. British volume
- Vol. 91-B (5) , 565-576
Abstract
Articular cartilage repair remains a challenge to surgeons and basic scientists. The field of tissue engineering allows the simultaneous use of material scaffolds, cells and signalling molecules to attempt to modulate the regenerative tissue. This review summarises the research that has been undertaken to date using this approach, with a particular emphasis on those techniques that have been introduced into clinical practice, via in vitro and preclinical studies.Keywords
This publication has 142 references indexed in Scilit:
- Comparison of Chondrogenic Potential in Equine Mesenchymal Stromal Cells Derived from Adipose Tissue and Bone MarrowVeterinary Surgery, 2008
- PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCsBiochemical and Biophysical Research Communications, 2008
- Concepts in gene therapy for cartilage repairInjury, 2008
- Forced expression of Sox2 or Nanog in human bone marrow derived mesenchymal stem cells maintains their expansion and differentiation capabilitiesExperimental Cell Research, 2008
- Induced Pluripotent Stem Cell Lines Derived from Human Somatic CellsScience, 2007
- Chondrocyte outgrowth into a gelatin scaffold in a single impact load model of damage/repair – effect of BMP-2BMC Musculoskeletal Disorders, 2007
- Mitogenic and chondrogenic effects of fibroblast growth factor-2 in adipose-derived mesenchymal cellsBiochemical and Biophysical Research Communications, 2006
- Challenges in tissue engineeringJournal of The Royal Society Interface, 2006
- Platelet derived growth factor stimulates chondrocyte proliferation but prevents endochondral maturationEndocrine, 1997
- Stimulation of cartilage‐matrix proteoglycan synthesis by morphologically transformed chondrocytes grown in the presence of fibroblast growth factor and transforming growth factor‐betaJournal of Cellular Physiology, 1989