Hydroxytyrosol inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines by the simultaneous targeting of epithelial-to-mesenchymal transition, Wnt/β-catenin and TGFβ signaling pathways
- 21 November 2018
- journal article
- research article
- Published by Springer Nature in European Journal of Nutrition
- Vol. 58 (8) , 3207-3219
Abstract
This study was aimed to determine the impact of hydroxytyrosol (HT), a minor compound found in olive oil, on breast cancer stem cells (BCSCs) and the migration capacity of triple-negative breast cancer (TNBC) cell lines through the alteration of epithelial-to-mesenchymal transition (EMT) and embryonic signaling pathways.Keywords
Funding Information
- Instituto de Salud Carlos III (CP14/00197, PI15/00336, PIE16/00045)
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