Design, synthesis, and inhibition of oxidative, amyloidogenic, and cholinergic dysfunction of saxagliptin-derived schiff bases against STZ-induced sporadic AD-like pathology
- 23 May 2026
- journal article
- Published by Elsevier in European Journal of Pharmacology
- Vol. 1028, 178987
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Plumbagin as a potential therapeutic agent for scopolamine-induced Alzheimer’s disease: Mechanistic insights into GSK-3β inhibitionBrain Research, 2025
- Repurposing drugs: promising therapeutic approach against Alzheimer’s diseaseAgeing Research Reviews, 2025
- Exploring DPP IV inhibitors for Alzheimer’s disease: Bridging diabetes and neurodegenerationBrain Research, 2024
- Animal model of Alzheimer’s disease induced by streptozotocin: New insights about cholinergic pathwayBrain Research, 2022
- Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammationBiomedicine & Pharmacotherapy, 2022
- Therapeutic efficacy of Clompanus pubescens leaves fractions via downregulation of neuronal cholinesterases/Na+-K+ATPase/IL-1 β, and improving the neurocognitive and antioxidants status of streptozotocin-induced diabetic ratsBiomedicine & Pharmacotherapy, 2022
- Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's diseaseBioorganic Chemistry, 2021
- 7,8-Dihydroxyflavone improves cognitive functions in ICV-STZ rat model of sporadic Alzheimer’s disease by reversing oxidative stress, mitochondrial dysfunction, and insulin resistancePsychopharmacology, 2021
- Swertiamarin and quercetin combination ameliorates hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced type 2 diabetes mellitus in wistar ratsBiomedicine & Pharmacotherapy, 2020
- Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer’s Disease: in Search of a Relevant MechanismMolecular Neurobiology, 2015