Running rings around protein cages: a case study of artificial TRAP cages
Authors:
- 2 February 2024
- book chapter
- Published by Royal Society of Chemistry (RSC)
- p. 45-63
Abstract
Proteins that constitute the capsids of viruses are well known for their ability to assemble into cage-like containers. Such containers can carry out useful tasks such as the delivery of cargoes to cells. Here we briefly review our work on naturally-occurring protein cages which were re-engineered to serve as containers. We focus on a completely artificial “TRAP-cage” and review its potential applications as a vaccine candidate and smart drug delivery system.Keywords
This publication has 66 references indexed in Scilit:
- Gold Nanoparticle-Induced Formation of Artificial Protein CapsidsNano Letters, 2012
- Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesinProceedings of the National Academy of Sciences, 2012
- The characterization of Thermotoga maritima ferritin reveals an unusual subunit dissociation behavior and efficient DNA protection from iron-mediated oxidative stressExtremophiles, 2011
- Stamped microbattery electrodes based on self-assembled M13 virusesProceedings of the National Academy of Sciences, 2008
- Immunogenic Display of Diverse Peptides on Virus-like Particles of RNA Phage MS2Journal of Molecular Biology, 2008
- Using the Ring‐Shaped Protein TRAP to Capture and Confine Gold Nanodots on a Surface.Small, 2007
- Effect of N-terminal Residues on the Structural Stability of Recombinant Horse L-chain Apoferritin in an Acidic EnvironmentThe Journal of Biochemistry, 2007
- The Interaction of RNA with TRAP: The Role of Triplet Repeats and Separating Spacer NucleotidesJournal of Molecular Biology, 2004
- The structure of trp RNA-binding attenuation proteinNature, 1995
- Physical Principles in the Construction of Regular VirusesCold Spring Harbor Symposia on Quantitative Biology, 1962