Autismo e epilepsia: modelos e mecanismos
Open Access
- 1 January 2012
- journal article
- Published by FapUNIFESP (SciELO) in Journal of Epilepsy and Clinical Neurophysiology
- Vol. 18 (3) , 92-96
Abstract
O autismo está associado a epilepsia em aproximadamente 30% dos casos com evidências sugerindo a mesma neurofisiopatologia. O mecanismo comum em ambas doenças ainda não está bem definido e a heterogeneidade dos sintomas clínicos nas crianças com transtorno do espectro autista e epilepsia reforça a importância de uma abordagem que inclui a investigação de etiologias biológicas através de estudos de neuroimagem, dos processos inflamatórios, de genética e neuroquímica. Aqui, iremos revisar os principais aspectos da associação entre autismo e epilepsia.Keywords
This publication has 41 references indexed in Scilit:
- Sign language in Landau‐Kleffner syndromeEpilepsia, 2009
- Gray and white matter imbalance – Typical structural abnormality underlying classic autism?Brain and Development, 2008
- Autism and Epilepsy: What Has Regression Got to Do with It?Epilepsy Currents, 2006
- Autism and epilepsy: Cause, consequence, comorbidity, or coincidence?Epilepsy & Behavior, 2005
- Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnectionCurrent Opinion in Neurobiology, 2005
- Autism and pervasive developmental disordersJornal de Pediatria, 2004
- Epilepsy in autismThe Lancet Neurology, 2002
- Functional neuroimaging and childhood autismPediatric Radiology, 2001
- Landau–Kleffner syndrome: sleep EEG characteristics at onsetClinical Neurophysiology, 2000
- Perfusion impairments in infantile autism on technetium-99m ethyl cysteinate dimer brain single-photon emission tomography: comparison with findings on magnetic resonance imagingEuropean Journal of Nuclear Medicine and Molecular Imaging, 1999