Sequence-Function Relationships in Phage-Encoded Bacterial Cell Wall Lytic Enzymes and Their Implications for Phage-Derived Product Design

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Abstract
Phage-encoded lytic enzymes, also called lysins, are one of the most promising alternatives to common antibiotics. The potential of lysins as novel antimicrobials to tackle antibiotic-resistant bacteria not only arises from features such as a lower chance to provoke resistance but also from their versatility as synthetic biology parts.
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  • Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
  • Ministerio de Economía, Industria y Competitividad, Gobierno de España (SAF2017-88664-R)

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