Substituted 1,3,5-Triazaadamantanes: Biocompatible and Degradable Building Blocks
- 29 September 2008
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition
- Vol. 47 (42) , 8072-8074
Abstract
Basic groups from acid hydrolysis : 1,3,5‐Triazaadamantanes (TAAs) are shown to degrade in acidic conditions to produce basic byproducts (see scheme). The rate of hydrolysis can be tuned by changing the substituents present on the aromatic rings. TAA‐containing dendrimers can be synthesized readily as a result of the branched architecture of the TAA building blocks.Keywords
This publication has 25 references indexed in Scilit:
- Biodegradable polymers as non-viral carriers for plasmid DNA deliveryJournal of Controlled Release, 2008
- Polymer carriers for drug delivery in tissue engineeringAdvanced Drug Delivery Reviews, 2007
- Polymer Therapeutics: Concepts and ApplicationsAngewandte Chemie International Edition, 2006
- Design and development of polymers for gene deliveryNature Reviews Drug Discovery, 2005
- Self‐Immolative DendrimersAngewandte Chemie, 2003
- “Cascade‐Release Dendrimers” Liberate All End Groups upon a Single Triggering Event in the Dendritic CoreAngewandte Chemie, 2003
- Propeller-Shaped Octupolar Molecules Derived from Triphenylbenzene for Nonlinear Optics: Synthesis and Optical StudiesChemistry of Materials, 2003
- A Simple Method for Controlling Dendritic Architecture and Diversity: A Parallel Monomer Combination ApproachThe Journal of Organic Chemistry, 2000
- Solvatochromic Dyes as Solvent Polarity IndicatorsChemical Reviews, 1994
- Anilinonaphthalene sulfonate as a probe of membrane composition and functionBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1982