Intraluminal micromanometry: an evaluation of the dynamic performance of micro‐extrusions and sleeve sensors

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Abstract
Conventional manometric techniques are unsuitable for studies in premature infants and small laboratory animals. We have therefore developed silicone rubber 5‐lumen and 10‐lumen micromanometric extrusions with an o.d. 2.0 mm and lumina of 0.35 mm i.d. This study evaluates the suitability of micro‐extrusions for intraluminal perfusion manometry.Pressure offset, post‐occlusion pressure rise rate and sphincter model studies were used to assess the monometric performance of the extrusions and a miniature sleeve sensor (25 mm long) at infusion rates of 0.01‐0.1 mL min−1.Micro‐extrusions (5‐lumen/10‐lumen, respectively) had offsets (per 100 cm of length) of 3.8/5.0 mmHg at 0.01 mL min−1 and 25.6/26.2 mmHg at 0.1 mL min−1 and rise rates (in 160 cm lengths) of 64/43 mmHg sec−1 at 0.01 mL min−1 and 330/224 mmHg sec−1 at 0.1 mL min−1. Infusion rates 0.025 mL min−1 produced rise rates 100 mmHg sec−1. The miniature sleeve sensor had minimal resistance to perfusion, rise rates of 3 mmHg sec−1 at 0.01 mL min−1 and 23 mmHg sec−1 at 0.1 mL min−1 and recorded pressure as accurately as a side hole.We conclude that the performance of micromanometric extrusions and sleeves is sufficient for intraluminal perfusion manometry.