Breaking in a New Function for Casein Kinase 2
Authors:
- 2 June 2004
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science of Aging Knowledge Environment
- Vol. 2004 (22) , pe24-24
Abstract
DNA damage response mechanisms help ensure the fidelity of chromosomal transmission, and the failure of such mechanisms might lead to premature aging and cancer. A new report has established that casein kinase 2 (CK2), a protein that functions in diverse cellular processes, controls the activity of the DNA repair protein XRCC1. These results indicate that CK2 is a key participant in the cellular response to DNA damage.Keywords
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