Neuroinflammation Detected by TSPO PET in Adult Onset Leukodystrophy With Axonal Spheroids and Pigmented Glia
Open Access
- 1 September 2026
- journal article
- Published by Wolters Kluwer Health in Neurology Open Access
- Vol. 2 (3) , e000131
Abstract
Background and ObjectivesAdult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP) causes a progressive neurodegenerative disease, with typical onset in the fourth decade of life. ...Keywords
This publication has 19 references indexed in Scilit:
- Heterozygous missense CSF1R variants hamper in vitro CD34+-derived dendritic cell generation but not in vivo dendritic cell developmentMolecular Immunology, 2024
- CSF1R-related disorder: State of the art, challenges, and proposition of a new terminologyParkinsonism & Related Disorders, 2023
- Report of A Family with Adult‐Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) Without Mutations in CSF1R, AARS1 or AARS2Movement Disorders Clinical Practice, 2023
- Using simultaneous PET/MRI to compare the accuracy of diagnosing frontotemporal dementia by arterial spin labelling MRI and FDG-PETNeuroImage: Clinical, 2018
- PETPVE12: an SPM toolbox for Partial Volume Effects correction in brain PET – Application to amyloid imaging with AV45-PETNeuroImage, 2017
- Analysis of Mutations in AARS2 in a Series of CSF1R-Negative Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented GliaJAMA Neurology, 2016
- In-vivo imaging of grey and white matter neuroinflammation in Alzheimer’s disease: a positron emission tomography study with a novel radioligand, [18F]-FEPPAMolecular Psychiatry, 2015
- Translocator Protein (18 kDa) Polymorphism (rs6971) Explains in-vivo Brain Binding Affinity of the PET Radioligand [18F]-FEPPAJournal of Cerebral Blood Flow & Metabolism, 2012
- Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroidsNature Genetics, 2011
- Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptorsNuclear Medicine and Biology, 2008