Biochemical and computational evaluation of Triptolide-induced cytotoxicity against NSCLC
- 1 July 2018
- journal article
- research article
- Published by Elsevier in Biomedicine & Pharmacotherapy
- Vol. 103, 1557-1566
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (81274146, 81773995, 81320108029)
- National “Major Scientific and Technological Special Project for Significant New Drugs” (2015ZX09501004-002-004)
- Specific Fund for Public Interest Research of Traditional Chinese Medicine, Ministry of finance (201507004-002)
This publication has 57 references indexed in Scilit:
- Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In VivoPLOS ONE, 2013
- The Paradox of Akt-mTOR InteractionsFrontiers in Oncology, 2013
- Apoptosis and Beyond: Cytometry in Studies of Programmed Cell Death2011
- Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase InhibitionPLOS ONE, 2010
- Triptolide Induces Cell Death in Pancreatic Cancer Cells by Apoptotic and Autophagic PathwaysGastroenterology, 2010
- MYC-Induced Cancer Cell Energy Metabolism and Therapeutic OpportunitiesClinical Cancer Research, 2009
- AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreadingJournal of Computational Chemistry, 2009
- Akt-dependent and -independent mechanisms of mTOR regulation in cancerCellular Signalling, 2009
- Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric InhibitionPLOS Biology, 2009
- UCSF Chimera—A visualization system for exploratory research and analysisJournal of Computational Chemistry, 2004