Methotrexate pharmacogenomics

This publication has 11 references indexed in Scilit:

• Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis
  Annals of the Rheumatic Diseases, 2006
• Risk genotypes in folate‐dependent enzymes and their association with methotrexate‐related side effects in rheumatoid arthritis
  Arthritis & Rheumatism, 2006
• Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis
  Arthritis & Rheumatism, 2004
• Toward a better understanding of methotrexate
  Arthritis & Rheumatism, 2004
• Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies
  American Heart Journal, 2003
• Pharmacogenetics and Folate Metabolism –a Promising Direction
  Pharmacogenomics, 2002
• Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
  Pharmacogenetics, 2002
• Genetic basis of neural tube defects. II. Genes correlated with folate and methionine metabolism.
  2002
• The C677T mutation in the methylenetetrahydrofolate reductase gene: A genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients
  Arthritis & Rheumatism, 2001
• Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism
  Blood, 2001