SOMATOCRININ (GRF) STIMULATES SECRETION OF BIOACTIVE SOMATHORMONE IN NORMAL ADULT MAN
Authors:
- G SASSOLASGSG SASSOLAS
- JP BOISSELJBJP BOISSEL
- R COHENRCR COHEN
- P CHATELAINPCP CHATELAIN
- S LAPORTESLS LAPORTE
- J GALLEYRANDJGJ GALLEYRAND
- H COHENHCH COHEN
- S FERRYSFS FERRY
- P MAIREPMP MAIRE
- 1 January 1983
- journal article
- research article
- Vol. 296 (23) , 1113-1116
Abstract
Injection i.v. of 4 doses (75, 150, 300, 600 .mu.g) of synthetic somatocrinin (GRF [growth hormone-releasing factor] 44) greatly increases serum growth hormone [GH] concentrations in 10 adult normal men in contrast to placebo. Mean peak values were identical. Plasma GH released under GRF stimulation was able to stimulate proliferation of [rat pituitary] NB2 cells.Keywords
This publication has 2 references indexed in Scilit:
- SOMATOCRININ INDUCES RELEASE OF GROWTH-HORMONE IN ONE CASE OF GROWTH-HORMONE DEFICIENCY OF HYPOTHALAMIC ORIGIN1983
- Somatocrinin, growth hormone releasing factor, stimulates secretion of growth hormone in anesthetized ratsBiochemical and Biophysical Research Communications, 1982