Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants
Open Access
- 9 November 2021
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 95 (23) , e0131321
Abstract
In light of multiple variants of SARS-CoV-2 that have been documented globally during the COVID-19 pandemic, it remains important to continually assess the ability of currently available vaccines to confer protection against newly emerging variants. Data presented herein indicate that immunization with the mRNA-1273 COVID-19 vaccine produces neutralizing antibodies against key emerging variants tested, including variants of concern and variants of interest.Keywords
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Funding Information
- Moderna, Inc.
This publication has 11 references indexed in Scilit:
- BNT162b2-Elicited Neutralization against New SARS-CoV-2 Spike VariantsNew England Journal of Medicine, 2021
- Potency of BNT162b2 and mRNA‐1273 vaccine‐induced neutralizing antibodies against severe acute respiratory syndrome‐CoV‐2 variants of concern: A systematic review of in vitro studiesReviews in Medical Virology, 2021
- BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variantsNature, 2021
- Serum Neutralizing Activity Elicited by mRNA-1273 VaccineNew England Journal of Medicine, 2021
- Neutralizing Activity of BNT162b2-Elicited SerumNew England Journal of Medicine, 2021
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 VaccineNew England Journal of Medicine, 2021
- Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older AdultsNew England Journal of Medicine, 2020
- An mRNA Vaccine against SARS-CoV-2 — Preliminary ReportNew England Journal of Medicine, 2020
- SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparednessNature, 2020
- Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccinesJournal of Virological Methods, 2010