Identifying differential correlation in gene/pathway combinations
Open Access
- 18 November 2008
- journal article
- research article
- Published by Springer Nature in BMC Bioinformatics
- Vol. 9 (1) , 488
Abstract
An important emerging trend in the analysis of microarray data is to incorporate known pathway information a priori. Expression level "summaries" for pathways, obtained from the expression data for the genes constituting the pathway, permit the inclusion of pathway information, reduce the high dimensionality of microarray data, and have the power to elucidate gene-interaction dependencies which are not already accounted for through known pathway identification.Keywords
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