On the Use of Iron in Organic Chemistry
Open Access
Abstract
Transition metal catalysis in modern organic synthesis has largely focused on noble transition metals like palladium, platinum and ruthenium. The toxicity and low abundance of these metals, however, has led to a rising focus on the development of the more sustainable base metals like iron, copper and nickel for use in catalysis. Iron is a particularly good candidate for this purpose due to its abundance, wide redox potential range, and the ease with which its properties can be tuned through the exploitation of its multiple oxidation states, electron spin states and redox potential. This is a fact made clear by all life on Earth, where iron is used as a cornerstone in the chemistry of living processes. In this mini review, we report on the general advancements in the field of iron catalysis in organic chemistry covering addition reactions, C-H activation, cross-coupling reactions, cycloadditions, isomerization and redox reactions.Keywords
Funding Information
- Vetenskapsrådet (2016-03897)
This publication has 72 references indexed in Scilit:
- The Continuing Puzzle of the Great Oxidation EventCurrent Biology, 2009
- Sustainable Metal Catalysis with Iron: From Rust to a Rising Star?Angewandte Chemie International Edition, 2008
- Enantioselective α-Hydroxylation of 2-Arylacetic Acid Derivatives and Buspirone Catalyzed by Engineered Cytochrome P450 BM-3Journal of the American Chemical Society, 2006
- Asymmetric amidation of saturated C–H bonds catalysed by chiral ruthenium and manganese porphyrinsChemical Communications, 1999
- Chemistry of dicarbonyl .eta.5-cyclopentadienyliron complexes. General syntheses of monosubstituted .eta.2-olefin complexes and of 1-substituted .eta.1-allyl complexes. Conformational effects on the course of deprotonation of (.eta.2-olefin) cationsJournal of the American Chemical Society, 1975
- π-Allyl-Iron Tricarbonyl CationsJournal of the American Chemical Society, 1962
- SYNTHESIS OF PHTHALIMIDINES FROM SCHIFF BASES AND CARBON MONOXIDEJournal of the American Chemical Society, 1955
- Carbonylierung I. Über die Umsetzung von Acetylen mit Kohlenoxyd und Verbindungen mit reaktionsfähigen Wasserstoffatomen Synthesen α,β‐ungesättigter Carbonsäuren und ihrer DerivateEuropean Journal of Organic Chemistry, 1953
- THE STRUCTURE OF IRON BIS-CYCLOPENTADIENYLJournal of the American Chemical Society, 1952
- LV.—Note on a volatile compound of iron with carbonic oxideJournal of the Chemical Society, Transactions, 1891