Nanofilaments on glioblastoma exosomes revealed by peak force microscopy
Open Access
- 6 March 2014
- journal article
- Published by The Royal Society in Journal of The Royal Society Interface
- Vol. 11 (92) , 20131150
Abstract
Exosomes are sub-100 nm extracellular vesicles secreted by normal and cancer cells. We present a high-resolution structure of previously unidentified nanofilaments on glioblastoma-derived exosomes, using nanoscale peak force imaging. These stiff, adhesive, trypsin- and RNAse-resistant surface nanofilaments add a new dimension to the current structural knowledge of exosome-mediated intercellular communication.Keywords
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