Industry and academic scientists view scientific and technical predicaments as fields that require an interdisciplinary method. With the increased interest about interdisciplinary research in universities, campus supervisory bodies must give considerable attention to this kind of inquiry. While a cross-disciplinary perspective provides positive contributions in both a conceptual and practical sense, there will always be conflicts encountered during the execution of such a type of research. Epistemological concerns and conceptual issues are implanted in the organizational and cognitive complexities of both academic and industrial institutions. Other problems arise from geographical barriers, time limitations, reciprocal neglect of the existence and needs of others, and lack of social orientation. In this regard, the chapter presents a theoretical paradigm that can explain the occurrence of conflicts and its management.