Gastric cancer: ESMO–ESSO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

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Abstract
In 2012, there were ∼140 000 new cases of gastric cancer diagnosed across all European countries, making it the sixth commonest cancer diagnosis. Perhaps more importantly, it remains the fourth commonest cause of cancer-related death, being responsible for ∼107 000 deaths annually [1]. Despite a gradual decline in the worldwide incidence of gastric cancer, there has been a relative increase in the incidence of tumours of the oesophago-gastric junction (OGJ) and gastric cardia. The peak incidence is in the seventh decade, and the disease is approximately twice as common in men as in women. There is a marked geographic variation, with the highest rates reported in East Asia, South America and Eastern Europe and the lowest rates in the United States and Western Europe [2].

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