Decrease of regulatory T cells in patients with systemic lupus erythematosus
- 1 April 2006
- journal article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 65 (4) , 553-554
Abstract
Thirty three patients with SLE (26 women, 7 men) and 14 healthy volunteers matched for age and sex (11 women, 3 men) with a mean age of 39.9 and 36 years, respectively, were studied. All patients fulfilled at least four of the American College of Rheumatology 1982 revised criteria for the classification of SLE.6 Disease activity at the time of blood sampling was assessed using the SLE Disease Activity Index (SLEDAI).7 …Keywords
This publication has 9 references indexed in Scilit:
- T cells in the pathogenesis of systemic lupus erythematosusClinical Immunology, 2004
- NaturallyArisingCD4+RegulatoryT Cells forImmunologicSelf-Tolerance andNegativeControl ofImmuneResponsesAnnual Review of Immunology, 2004
- Decreased CD4+CD25+ T Cells in Peripheral Blood of Patients with Systemic Lupus ErythematosusScandinavian Journal of Immunology, 2004
- Quantification of regulatory T cells in patients with systemic lupus erythematosusJournal of Autoimmunity, 2003
- CD4+CD25high Regulatory Cells in Human Peripheral BloodThe Journal of Immunology, 2001
- Regulatory T Cells in AutoimmmunityAnnual Review of Immunology, 2000
- Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesThe Journal of Immunology, 1995
- Derivation of the sledai. A disease activity index for lupus patientsArthritis & Rheumatism, 1992
- The 1982 revised criteria for the classification of systemic lupus erythematosusArthritis & Rheumatism, 1982