RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.
Authors:
- C DuncanCDC Duncan
- P A BiroPBP A Biro
- P V ChoudaryPCP V Choudary
- J T ElderJEJ T Elder
- R R WangRWR R Wang
- B G ForgetBFB G Forget
- J K de RielJRJ K de Riel
- S M WeissmanSWS M Weissman
Open Access
- 1 October 1979
- journal article
- research article
- Published by National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (10) , 5095-5099
Abstract
Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species. One transcription unit is located approximately 1500 base pairs upstream from the G-gamma-globin gene. This transcript is partially homologous to a polymerase III template located approximately 1000 base pairs upstream from the delta-globin gene and to DNA located a short distance downstream from the beta-globin gene.Keywords
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