Bioactive Phenolic Amides from Celtis africana
Open Access
- 5 March 2012
- Vol. 17 (3) , 2675-2682
Abstract
Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1–3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity.Keywords
This publication has 11 references indexed in Scilit:
- Antioxidant and urease inhibitoryC-glycosylflavonoids fromCeltis africanaJournal of Asian Natural Products Research, 2011
- Isolation and Characterization ofN-Feruloyltyramine as the P-Selectin Expression Suppressor from Garlic (Allium sativum)Journal of Agricultural and Food Chemistry, 2009
- Isolation and Pharmacological Characterization of Fatty Acids from Saw Palmetto ExtractAnalytical Sciences, 2009
- Ethnomedicinal and bioactive properties of plants ingested by wild chimpanzees in UgandaJournal of Ethnopharmacology, 2005
- Determination of in Vitro Antioxidant and Radical Scavenging Activities of PropofolChemical and Pharmaceutical Bulletin, 2005
- Determination of the fatty acid profile by 1H‐NMR spectroscopyEuropean Journal of Lipid Science and Technology, 2004
- Carrageenan-Induced Paw Edema in the Rat and Mouse2003
- Isolation and Activity ofN-p-Coumaroyltyramine, anα-Glucosidase Inhibitor in Welsh Onion (Allium fistulosum)Bioscience, Biotechnology, and Biochemistry, 1997
- Bioactive Constitutents from the Stems ofAnnona montanaPlanta Medica, 1995
- A new and rapid colorimetric determination of acetylcholinesterase activityBiochemical Pharmacology, 1961