Congenital microvillous atrophy: specific diagnostic features.
Authors:
- A D PhillipsAPA D Phillips
- P JenkinsPJP Jenkins
- F RaafatFRF Raafat
- J A Walker-SmithJWJ A Walker-Smith
- 1 February 1985
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 60 (2) , 135-140
Abstract
Proximal small intestinal and colonoscopic mucosal biopsies from two children with the intractable diarrhea of infancy syndrome were examined by electron microscopy. Microvillous involutions were found in the small and large bowel of both patients. We suggest that this is a specific diagnostic finding for congenital microvillous atrophy, a distinct disorder within the intractable diarrhoea syndrome which has an extremely poor prognosis.Keywords
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