Emerging techniques in the isolation and characterization of extracellular vesicles and their roles in cancer diagnostics and prognostics
Authors:
Open Access
- 26 October 2015
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 141 (2) , 371-381
Abstract
We present an overview of current isolation, detection, and characterization methods of extracellular vesicles and their applications and limitations as a potential emerging biomarker in cancer management and their clinical implementation.Keywords
Funding Information
- National Research Foundation of Korea (2013R1A2A2A05004314, 2012R1A1A2043747)
This publication has 95 references indexed in Scilit:
- Increased Exosomal MicroRNA-21 and MicroRNA-146a Levels in the Cervicovaginal Lavage Specimens of Patients with Cervical CancerInternational Journal of Molecular Sciences, 2014
- Exosomes in Prostate Cancer: Putting Together the Pieces of a PuzzleCancers, 2013
- Proteome Profiling of Neuroblastoma-Derived Exosomes Reveal the Expression of Proteins Potentially Involved in Tumor ProgressionPLOS ONE, 2013
- Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate CancerPLOS ONE, 2013
- Intercellular Communication by Exosome-Derived microRNAs in CancerInternational Journal of Molecular Sciences, 2013
- Detection of exosomal biomarker by electric field-induced release and measurement (EFIRM)Biosensors and Bioelectronics, 2013
- Extracellular vesicle sizing and enumeration by nanoparticle tracking analysisJournal of Extracellular Vesicles, 2013
- Determination of the size distribution of blood microparticles directly in plasma using atomic force microscopy and microfluidicsBiomedical Microdevices, 2012
- Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune cellsImmunology, 2012
- Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cellsNature Cell Biology, 2007