Induction in vitro of Microtubular Crystals by Vinca Alkaloids
Authors:
- 1 August 1969
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 165 (3892) , 495-496
Abstract
The addition of vinblastine or vincristine to solutions of pure microtubule protein or to supernatants from high-speed centrifugation of rabbit-brain homogenates results in the formation of a fine precipitate. Examination of this precipitate by electron microscopy reveals ordered structures with areas of ladder-like configuration.Keywords
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