Diagnostic Value of Plasma Pentraxin-3 in Acute Appendicitis
- 11 October 2017
- journal article
- research article
- Published by Taylor & Francis in Journal of Investigative Surgery
- Vol. 32 (2) , 143-148
Abstract
Purpose: To measure serum PTX3 levels in patients admitted with right lower quadrant pain to emergency department and to investigate whether this parameter will be helpful for the diagnosis of acute appendicitis. Materials and methods: This study was conducted with a group of 89 patients over 17 years of age who were admitted with the complaint of right lower quadrant pain to ED and had a preliminary diagnosis of acute appendicitis clinically and the control group of 31 healthy volunteers in a tertiary university hospital for 3 months. Results: Median PTX3 levels were 3.28 (1.08-30.24) ng/mL in the acute appendicitis groups and 0.97 (0.34-2.62) ng/mL in the control group. A significant difference was observed between acute appendicitis groups and the control group (p < 0.05). Conclusion: PTX3 was found to be significantly higher in patient with acute appendicitis compared to the control group and the patients with non-specific abdominal pain. PTX3 can be used as an aid in the diagnosis of acute appendicitis.Keywords
This publication has 14 references indexed in Scilit:
- The yin-yang of long pentraxin PTX3 in inflammation and immunityImmunology Letters, 2014
- Biomarkers in the diagnosis of acute appendicitisJournal of Clinical and Experimental Investigations, 2014
- Systematic review and meta-analysis of the diagnostic accuracy of procalcitonin, C-reactive protein and white blood cell count for suspected acute appendicitisBritish Journal of Surgery, 2013
- Reliability of ultrasonography for diagnosing acute appendicitisTurkish Journal of Trauma and Emergency Surgery, 2011
- Akute AppendizitisDer Chirurg, 2009
- Total leucocyte count, C-reactive protein and neutrophil count: Diagnostic Aid in acute appendicitisSaudi Journal of Gastroenterology, 2009
- LABORATORY TESTS IN PATIENTS WITH ACUTE APPENDICITISAnz Journal of Surgery, 2006
- PENTRAXINS AT THE CROSSROADS BETWEEN INNATE IMMUNITY, INFLAMMATION, MATRIX DEPOSITION, AND FEMALE FERTILITYAnnual Review of Immunology, 2005
- Toll-like receptors in the pathogenesis of human diseaseNature Immunology, 2004
- Expression and production of the long pentraxin PTX3 in rheumatoid arthritis (RA)Clinical and Experimental Immunology, 2000