Progress in the development of ERK1/2 inhibitors for treating cancer and other diseases
Authors:
- 24 April 2024
- book chapter
- Published by Elsevier
- Vol. 100, 181-207
Abstract
No abstract availableKeywords
This publication has 120 references indexed in Scilit:
- Results of an open-label phase 1b study of the ERK inhibitor MK-8353 plus the MEK inhibitor selumetinib in patients with advanced or metastatic solid tumorsInvestigational New Drugs, 2023
- Characterization and management of ERK inhibitor associated dermatologic adverse events: analysis from a nonrandomized trial of ulixertinib for advanced cancersInvestigational New Drugs, 2021
- Structure–activity relationship study of DEL-22379: ERK dimerization inhibitors with increased safetyMolecular Diversity, 2020
- Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignanciesCancer Chemotherapy and Pharmacology, 2018
- Cardiovascular Effects of the MEK Inhibitor, Trametinib: A Case Report, Literature Review, and Consideration of MechanismCardiovascular Toxicology, 2017
- The MAP Kinase Signaling Cascades: A System of Hundreds of Components Regulates a Diverse Array of Physiological Functions2010
- B-RAF Inhibitors: An Evolving Role in the Therapy of Malignant MelanomaCurrent Oncology Reports, 2010
- Dual-specificity MAP kinase phosphatases (MKPs) and cancerCancer and Metastasis Reviews, 2008
- Activation of Raf-1 in Human Pancreatic AdenocarcinomaJournal of Surgical Research, 1997
- ERK phosphorylation potentiates Elk‐1‐mediated ternary complex formation and transactivation.The EMBO Journal, 1995