Advances in the generation of insertion-based genome edits in plants

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Abstract
Plant scientists and breeders strive to reduce poverty and undernourishment by increasing agricultural productivity and providing sufficient and nutritious food. The global human population is predicted to reach 10 billion by 2050, and crop production will need to be double that of 2005 (Tilman et al., 2011). However, agricultural productivity is faced with numerous constraints such as climate change, reduced arable land, and shortage of water resources. Therefore, there are increasing demands to generate new crop varieties with improved traits, such as disease resistance, stress tolerance, and efficient resource usage, in order to develop environmental-friendly sustainable agriculture, while maintaining high quality and nutrient-rich food for a better quality of life. To overcome these challenges, there is an urgent need to develop innovative and efficient crop breeding techniques to generate better varieties for increasing agricultural productivity.

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