Enantioselective difunctionalization of alkenes by a palladium-catalyzed Heck/borylation sequence
Open Access
- 22 January 2022
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Science
- Vol. 13 (7) , 2021-2025
Abstract
A palladium catalyzed enantioselective Heck/borylation reaction of alkene-tethered aryl iodides was realized, delivering a variety of 2,3-dihydrobenzofuranyl boronic esters in high yield with excellent enantioselectivity.Keywords
Funding Information
- National Natural Science Foundation of China (21801078, 21921003, 22031004, 22071060)
- E-Institutes of Shanghai Municipal Education Commission (20212308)
- Shanghai Municipal Education Commission
This publication has 62 references indexed in Scilit:
- Functional group directed C–H borylationChemical Society Reviews, 2014
- Transition-metal-catalyzed Suzuki–Miyaura cross-coupling reactions: a remarkable advance from palladium to nickel catalystsChemical Society Reviews, 2013
- A synthetic approach for (S)-(3-benzyl-3-methyl-2,3-dihydro-benzofuran-6-yl)-piperidin-1-yl-methanone, a selective CB2 receptor agonistTetrahedron Letters, 2012
- Synthesis of New 4,5-Dihydrofuranoindoles and Their Evaluation as HCV NS5B Polymerase InhibitorsOrganic Letters, 2012
- 2,3‐Dihydro‐1‐Benzofuran Derivatives as a Series of Potent Selective Cannabinoid Receptor 2 Agonists: Design, Synthesis, and Binding Mode Prediction through Ligand‐Steered ModelingChemMedChem, 2009
- Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivativesBioorganic & Medicinal Chemistry Letters, 2008
- Synthesis of Diversely Functionalized Hexahydropyrrolo[2,3-b]indoles Using Domino Reactions, Olefination, Isomerization and Claisen Rearrangement Followed by Reductive CyclizationThe Journal of Organic Chemistry, 2005
- Studies toward Diazonamide A: Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed StructureJournal of the American Chemical Society, 2004
- Metal‐catalyzed reactions of diborons for synthesis of organoboron compoundsThe Chemical Record, 2004
- Organoboron Compounds2002