Fundus autofluorescence in patients with blunt ocular trauma
- 10 November 2009
- journal article
- Published by Wiley in Acta Ophthalmologica
- Vol. 89 (1) , e89-e94
Abstract
Purpose: To report fundus autofluorescence and optical coherence tomography (OCT) findings in patients with blunt ocular trauma.Methods: Six eyes of six consecutive patients with blunt ocular trauma were evaluated in an observational case series using colour fundus photography, the Heidelberg Retina Angiograph 2 (HRA2) system for fundus autofluorescence (FAF) and OCT (Stratus OCT).Results: Three patients presented with secondary retinal pigment epitheliopathy that was identified as a reduced FAF plaque with interposed increased FAF granular smaller lesions. These findings were not as evident in fundus examination and colour photography in two patients. Visual field in one patient showed a decreased area of sensitivity that correlated to the reduced/increased autofluorescent lesion. the other three patients had subretinal haemorrhage and choroidal rupture, which appeared with a reduced FAF with an increased FAF rim after resolution. OCT demonstrated a choriocapillaris/retinal pigment epithelium (RPE) complex disruption and its resolution over time in all patients with choroidal rupture.Conclusion: Damaged RPE area was more evident and better delineated by FAF imaging compared with fundus examination and fundus photography alone. Autofluorescence imaging might be a useful exam to show the length and severity of post-traumatic retinal lesions and it may add relevant information in the global evaluation of blunt ocular trauma complications. Moreover, OCT added valuable information to the diagnosis and progression of choroidal rupture. Further studies to determine the predictive value of FAF in ocular blunt trauma are warranted.Universidade Federal de São Paulo, Vis Inst, Dept Ophthalmol, São Paulo, BrazilHosp Olhos de Araraquara, Retinal Diagnost & Treatment Div, São Paulo, BrazilUniversidade Federal de São Paulo, Vis Inst, Dept Ophthalmol, São Paulo, BrazilWeb of SciencKeywords
This publication has 12 references indexed in Scilit:
- Fundus Near Infrared Fluorescence Correlates with Fundus Near Infrared ReflectanceInvestigative Ophthalmology & Visual Science, 2006
- DIGITAL SIMULTANEOUS FLUORESCEIN AND INDOCYANINE GREEN ANGIOGRAPHY, AUTOFLUORESCENCE, AND RED-FREE IMAGING WITH A SOLID-STATE LASER-BASED CONFOCAL SCANNING LASER OPHTHALMOSCOPERetina, 2005
- RPE lipofuscin and its role in retinal pathobiologyExperimental Eye Research, 2005
- Fundus Autofluorescence and Fundus Perimetry in the Junctional Zone of Geographic Atrophy in Patients with Age-Related Macular DegenerationInvestigative Ophthalmology & Visual Science, 2004
- Reproducibility of fundus autofluorescence measurements obtained using a confocal scanning laser ophthalmoscopeBritish Journal of Ophthalmology, 1999
- Distribution of fundus autofluorescence with a scanning laser ophthalmoscope.British Journal of Ophthalmology, 1995
- Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent?Biochemical Journal, 1988
- CHOROIDAL RUPTURERetina, 1984
- Traumatic Retinal Pigment Epithelial EdemaAmerican Journal of Ophthalmology, 1979
- Traumatic Retinopathy in PrimatesArchives of Ophthalmology (1950), 1978