Imaging in acute renal infection in children

Authors:
  • JSJ R Sty
    J R Sty
  • RWRg Wells
    Rg Wells
  • RSRj Starshak
    Rj Starshak
  • BSBa Schroeder
    Ba Schroeder
  • JSJr Sty
    Jr Sty
  • PKP J Kenney
    P J Kenney
  • WLWing Hang Luk
    Wing Hang Luk
  • YWYip Hin Woo
    Yip Hin Woo
  • AAAndrea Wai San Au-Yeung
    Andrea Wai San Au-Yeung
  • JCJames Chi Sang Chan
    James Chi Sang Chan
  • EBE Björgvinsson
    E Björgvinsson
  • MMM Majd
    M Majd

Abstract
Infection is the most common disease of the urinary tract in children, and various imaging techniques have been used to verify its presence and location. On retrospective analysis, 50 consecutive children with documented upper urinary tract infection had abnormal findings on renal cortical scintigraphy with 99mTc-glucoheptonate. The infection involved the renal poles only in 38 and the poles plus other renal cortical areas in eight. Four had abnormalities that spared the poles. Renal sonograms were abnormal in 32 of 50 children. Excretory urograms were abnormal in six of 23 children in whom they were obtained. Vesicoureteral reflux was found in 34 of 40 children in whom voiding cystourethrography was performed. These data show the high sensitivity of renal cortical scintigraphy with 99mTc-glucoheptonate in documenting upper urinary tract infection. The location of the abnormalities detected suggests that renal infections spread via an ascending mode and implies that intrarenal reflux is a major contributing factor.

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