Induction of cell-cell fusion by ectromelia virus is not inhibited by its fusion inhibitory complex
Open Access
- 29 September 2009
- journal article
- Published by Springer Nature in Virology Journal
- Vol. 6 (1) , 151
Abstract
Ectromelia virus, a member of the Orthopox genus, is the causative agent of the highly infectious mousepox disease. Previous studies have shown that different poxviruses induce cell-cell fusion which is manifested by the formation of multinucleated-giant cells (polykaryocytes). This phenomenon has been widely studied with vaccinia virus in conditions which require artificial acidification of the medium.Keywords
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