The use of 1H NMR for yield determination in the regioselective epoxidation of squalene
- 1 June 2005
- journal article
- Published by Wiley in Journal of the American Oil Chemists' Society
- Vol. 82 (6) , 409-413
Abstract
1H NMR can be used to determine the epoxide yield rapidly in the oxidation of squalene. Moreover, unequivocal distinction can be made between internal and terminal epoxide bonds. To underline the power of this technique, different stoichiometric and catalytic epoxidation procedures were carried out using squalene as substrate. They were characterized in terms of substrate conversion and regioselectivity of the epoxide fraction.Keywords
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