Basal and stress-activated hypothalamic pituitary adrenal axis function in postmenopausal women with overactive bladder
Authors:
- 4 March 2016
- journal article
- research article
- Published by Springer Nature in International Urogynecology Journal
- Vol. 27 (9) , 1383-1391
Abstract
The aim of this study was to measure physiologic and psychologic stress reactivity in women with overactive bladder (OAB). There is growing evidence in preclinical models that central nervous system dysregulation, particularly in response to psychological stress, may contribute to lower urinary tract symptoms in women with OAB.Keywords
Funding Information
- National Institutes of Health (R01 AG048839, NIH P50 MH099910, R01 AG048839, K24 DA030301)
- National Institute of Diabetes and Digestive and Kidney Diseases (P50 DK052620-15)
This publication has 32 references indexed in Scilit:
- Sex differences in stress-related receptors: ″micro″ differences with ″macro″ implications for mood and anxiety disordersBiology of Sex Differences, 2013
- Hair Cortisol Level as a Biomarker for Altered Hypothalamic-Pituitary-Adrenal Activity in Female Adolescents with Posttraumatic Stress Disorder After the 2008 Wenchuan EarthquakeBiological Psychiatry, 2012
- The Effects of Acute and Chronic Psychological Stress on Bladder Function in a Rodent ModelUrology, 2011
- The bladder–brain connection: putative role of corticotropin-releasing factorNature Reviews Urology, 2010
- Predictors of discontinuing overactive bladder medicationsBJU International, 2010
- Social stress-induced bladder dysfunction: potential role of corticotropin-releasing factorAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2009
- The impact of overactive bladder, incontinence and other lower urinary tract symptoms on quality of life, work productivity, sexuality and emotional well‐being in men and women: results from the EPIC studyBJU International, 2008
- Education modulates cortisol reactivity to the Trier Social Stress Test in middle-aged adultsPsychoneuroendocrinology, 2007
- The standardisation of terminology of lower urinary tract function: Report from the standardisation sub‐committee of the International Continence SocietyNeurourology and Urodynamics, 2002
- The ‘Trier Social Stress Test’ – A Tool for Investigating Psychobiological Stress Responses in a Laboratory SettingNeuropsychobiology, 1993