Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists
- 1 March 2018
- journal article
- research article
- Published by Elsevier in European Journal of Pharmaceutical Sciences
- Vol. 114, 155-165
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- In Vitro–In Vivo Correlation of the Inhibition Potency of Sodium-Glucose Cotransporter Inhibitors in Rat: A Pharmacokinetic and Pharmacodynamic Modeling ApproachThe Journal of Pharmacology and Experimental Therapeutics, 2013
- Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent MechanismsArteriosclerosis, Thrombosis, and Vascular Biology, 2012
- Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissueAmerican Journal of Physiology-Endocrinology and Metabolism, 2011
- Biological Roles and Therapeutic Potential of Hydroxy-Carboxylic Acid ReceptorsFrontiers in Endocrinology, 2011
- Feedback modeling of non-esterified fatty acids in rats after nicotinic acid infusionsJournal of Pharmacokinetics and Pharmacodynamics, 2010
- The mechanism and mitigation of niacin-induced flushingInternational Journal Of Clinical Practice, 2009
- A Model of NEFA Dynamics with Focus on the Postprandial StateAnnals of Biomedical Engineering, 2009
- Role of GPR81 in lactate-mediated reduction of adipose lipolysisBiochemical and Biophysical Research Communications, 2008
- Elucidation of signaling and functional activities of an orphan GPCR, GPR81Journal of Lipid Research, 2008
- Correlation betweenin vitroandin vivoconcentration–effect relationships of naproxen in rats and healthy volunteersBritish Journal of Pharmacology, 2006