A Convenient Protocol for the α-Iodination of α,β-Unsaturated Carbonyl Compounds with I2 in an Aqueous Medium

Authors:
  • MKMarie E. Krafft
    Marie E. Krafft
  • JCJohn W. Cran
    John W. Cran
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Abstract
A variety of cyclic and acyclic α,β-unsaturated carbonyl compounds undergo α-iodination exclusively, in high yields, with I2 in aqueous THF catalyzed by DMAP and quinuclidine.