Effects of Helicobacter pylori Eradication on Methylation Status of E-Cadherin Gene in Noncancerous Stomach
Open Access
- 15 May 2006
- journal article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 12 (10) , 3216-3221
Abstract
Purpose: Promoter hypermethylation of E-cadherin plays an important role on gastric cancer development. Whereas E-cadherin methylation was frequently detected in the stomach of Helicobacter pylori–infected individuals, we tested whether eradication of H. pylori alters the methylation status of the noncancerous gastric epithelium.Keywords
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