Effect of Verification Bias on Screening for Prostate Cancer by Measurement of Prostate-Specific Antigen
Authors:
- Anthony V. D'AMicoADAnthony V. D'AMico
- William J. CatalonaWCWilliam J. Catalona
- Kimberly A. RoehlKRKimberly A. Roehl
- Karen M. KuntzKKKaren M. Kuntz
- 24 July 2003
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 349 (4) , 335-342
Abstract
The sensitivity and specificity of a screening test are biased when disease status is not verified in all subjects and when the likelihood of confirmation depends on the test result itself. We assessed the screening characteristics of the prostate-specific antigen (PSA) measurement after correction for verification bias.Keywords
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