Abstract
The major public health concern during the past 50 years has been coronary heart disease (CHD), which has been the leading cause of death in the UK and other nations in the temperate parts of the world, in particular northern Europe and North America. It has run in families and it has brought to a premature end the lives of people in their prime. It has robbed wives of their husbands and husbands of their wives. It has robbed children of their parents and sometimes parents of their children.