Reliable enumeration of malaria parasites in thick blood films using digital image analysis
Author:
Open Access
- 23 September 2009
- journal article
- research article
- Published by Springer Nature in Malaria Journal
- Vol. 8 (1) , 218
Abstract
Quantitation of malaria parasite density is an important component of laboratory diagnosis of malaria. Microscopy of Giemsa-stained thick blood films is the conventional method for parasite enumeration. Accurate and reproducible parasite counts are difficult to achieve, because of inherent technical limitations and human inconsistency. Inaccurate parasite density estimation may have adverse clinical and therapeutic implications for patients, and for endpoints of clinical trials of anti-malarial vaccines or drugs. Digital image analysis provides an opportunity to improve performance of parasite density quantitation.Keywords
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