Bond energy enabled amine distinguishing strategy: chemo-, regioselective 1,3-diamination of (trifluoromethyl)alkenes with different amines by two C(sp 3 )–F bond cleavages
- 24 January 2022
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic Chemistry Frontiers
- Vol. 9 (5) , 1383-1388
Abstract
ipso -Defluorinative amination-triggered 1,3-diamination of (trifluoromethyl)alkenes with different amines affords various monofluoroalkenylated acyclic 1,3-diamines in high yields with excellent Z / E selectivity.Keywords
Funding Information
- Basic and Applied Basic Research Foundation of Guangdong Province (2020B1515020012)
- National Natural Science Foundation of China (21702064)
- South China University of Technology (j2tw2021020004)
- National Key Research and Development Program of China (2016YFA0602900)
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