Hopeanol: A Potent Cytotoxin with A Novel Skeleton from Hopea exalata
Authors:
- 4 December 2006
- journal article
- research article
- Published by Wiley in European Journal of Organic Chemistry
- Vol. 2006 (24) , 5551-5554
Abstract
Hopeanol, a rearranged resveratrol dimer ester with an unprecedent carbon skeleton, was isolated from the bark ofHopea exalata. Its structure was determined by comprehensive spectroscopic analysis. Hopeanol exhibited potent cytotoxicity against six human cancer cell lines with its IC50 = 0.52–19.36 μM. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)Keywords
This publication has 13 references indexed in Scilit:
- Aspergillus fumigatus CY018, an endophytic fungus in Cynodon dactylon as a versatile producer of new and bioactive metabolitesJournal of Biotechnology, 2004
- Neoverataline A and B, two antifungal alkaloids with a novel carbon skeleton from Veratrum talienseTetrahedron, 2003
- Two new oligostilbenes with dihydrobenzofuran from the stem bark of Vateria indicaTetrahedron, 2003
- Antimicrobial Resveratrol Tetramers from the Stem Bark of Vatica oblongifolia ssp. oblongifoliaJournal of Natural Products, 2002
- Antifungal cyclopeptides from Halobacillus litoralis YS3106 of marine originTetrahedron Letters, 2002
- Vaticanol C, a Novel Resveratrol Tetramer, Inhibits Cell Growth through Induction of Apoptosis in Colon Cancer Cell Lines.Biological and Pharmaceutical Bulletin, 2002
- Four Novel Oligostilbenes from the Roots of Vitis amurensisTetrahedron, 2000
- HIV-Inhibitory and Cytotoxic Oligostilbenes from the Leaves of Hopea malibatoJournal of Natural Products, 1998
- (+)-.ALPHA.-Viniferin, an anti-inflammatory compound from Caragana chamlagu root.Chemical and Pharmaceutical Bulletin, 1990
- Further evidence for the structure of vaticaffinol and a revision of its stereochemistryPhytochemistry, 1987