Cell Cycle- and Ribonucleotide Reductase-Driven Changes in mtDNA Copy Number Influence mtDNA Inheritance Without Compromising Mitochondrial Gene Expression
Open Access
- 15 August 2007
- journal article
- Published by Taylor & Francis in Cell Cycle
- Vol. 6 (16) , 2048-2057
Abstract
Most eukaryotes maintain multiple copies of mtDNA, ranging from 20-50 in yeast to as many as 10,000 in mammalian cells. The mitochondrial genome encodes essential subunits of the respiratory chain,...Keywords
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