Controlling the toxicity of biomass-derived difunctional molecules as potential pharmaceutical ingredients for specific activity toward microorganisms and mammalian cells
- 21 April 2023
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Green Chemistry
- Vol. 25 (14) , 5416-5427
Abstract
A biomass-derived difuran molecule can be converted to difunctional compounds by Diels–Alder reaction with N -substituted maleimides. Acid-catalyzed retro Diels–Alder reaction of difunctional compounds can promote the eradication of microorganisms.Keywords
Funding Information
- U.S. Department of Energy (DE-SC0014058)
- U.S. Department of Energy (DE-SC0018409)
- National Science Foundation (CHE-1953926)
- National Institutes of Health (5T32GM135066-02)
- National Institutes of Health (R33AI127442)
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