Magnetic nanoparticle-mediated hyperthermia: From heating mechanisms to cancer theranostics
Open Access
- 1 January 2024
- journal article
- review article
- Published by Innovation Press Co., Limited in The Innovation Materials
- Vol. 2 (1) , 100051-1-100051-16
Abstract
Magnetic nanoparticle-mediated hyperthermia (MHT) is a promising tumor theranostic technology due to its noninvasive nature and ability to penetrate deep tissues without greatly damaging normal tissues. To advance the clinical translation and application of MHT, we present a comprehensive overview of topics related to MHT, including the basic physical heating principles, magnetic nanoparticle design, biological effects and theranostic applications. First, the fundamental physical principles through which magnetic nanoparticles mediate hyperthermia are reviewed in detail. Subsequently, strategies to increase the magnetothermal effect and biological effects of MHT are highlighted. Then, MHT and multitechnology integration applications in precision diagnosis and treatment are introduced. Finally, the key challenges and outlooks of MHT for clinical purposes are discussed.Keywords
This publication has 161 references indexed in Scilit:
- Programmed Catalytic Therapy and Antigen Capture‐Mediated Dendritic Cells Harnessing Cancer Immunotherapies by In Situ‐Forming Adhesive NanoreservoirsAdvanced Functional Materials, 2022
- A Strategy of Limited‐Space Controlled Aggregation for Generic Enhancement of Drug Loading CapabilityAdvanced Functional Materials, 2022
- Spatiotemporal Magnetocaloric Microenvironment for Guiding the Fate of Biodegradable Polymer ImplantsAdvanced Functional Materials, 2021
- Magnetothermal Multiplexing for Selective Remote Control of Cell SignalingAdvanced Functional Materials, 2020
- Magnetic Hyperthermia–Synergistic H2O2 Self‐Sufficient Catalytic Suppression of Osteosarcoma with Enhanced Bone‐Regeneration Bioactivity by 3D‐Printing Composite ScaffoldsAdvanced Functional Materials, 2019
- Magnetic (Hyper)Thermia or Photothermia? Progressive Comparison of Iron Oxide and Gold Nanoparticles Heating in Water, in Cells, and In VivoAdvanced Functional Materials, 2018
- Genetically Controlled Lysosomal Entrapment of Superparamagnetic Ferritin for Multimodal and Multiscale Imaging and Actuation with Low Tissue AttenuationAdvanced Functional Materials, 2018
- Toroidal Protein Adaptor Assembles Ferrimagnetic Nanoparticle Fibers with Constructive Magnetic CouplingAdvanced Functional Materials, 2017
- Nanoscale Thermal Phenomena in the Vicinity of Magnetic Nanoparticles in Alternating Magnetic FieldsAdvanced Functional Materials, 2016
- Smart Ferrofluid with Quick Gel Transformation in Tumors for MRI‐Guided Local Magnetic ThermochemotherapyAdvanced Functional Materials, 2016