Reducing the Incidence of Non-A,Non-B Post-Transfusion Hepatitis by Testing Donor Blood for Alanine Aminotransferase

Authors:
  • MHMark C. Hornbrook
    Mark C. Hornbrook
  • RDRoger Y. Dodd
    Roger Y. Dodd
  • PJPhilip Jacobs
    Philip Jacobs
  • LFLeonard I. Friedman
    Leonard I. Friedman
  • KSKenneth E. Sherman
    Kenneth E. Sherman

Abstract
Recent studies have established a relation between elevated alanine aminotransferase levels in donor blood and the incidence of non-A,non-B hepatitis in recipients of such blood. Routine testing of donor blood for alanine aminotransferase activity in order to reduce hepatitis is not currently supported, largely because the results of such testing are unknown.

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