Discovery of cyclic guanidine-linked sulfonamides as inhibitors of LMTK3 kinase
- 1 May 2020
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 30 (9) , 127108
Abstract
No abstract availableKeywords
Funding Information
- National Cancer Institute (1R21CA191351-01A1)
This publication has 29 references indexed in Scilit:
- LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanomaOncogene, 2018
- LMTK3 confers chemo-resistance in breast cancerOncogene, 2018
- Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsionNature Communications, 2017
- The Kinase LMTK3 Promotes Invasion in Breast Cancer Through GRB2-Mediated Induction of Integrin β 1Science Signaling, 2014
- LMTK3 is implicated in endocrine resistance via multiple signaling pathwaysOncogene, 2012
- Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargoOncogene, 2011
- Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancerNature Medicine, 2011
- Vascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant β-Catenin Activation in Colon CancerClinical Cancer Research, 2009
- RNAi screen for rapid therapeutic target identification in leukemia patientsProceedings of the National Academy of Sciences, 2009
- Peptide Microarray Analysis of Substrate Specificity of the Transmembrane Ser/Thr Kinase KPI-2 Reveals Reactivity with Cystic Fibrosis Transmembrane Conductance Regulator and PhosphorylaseMolecular & Cellular Proteomics, 2006